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Games, Games, Games

While I don't have much energy for playing a lot anymore, I do like to keep some track of them and have information handy. It's all a bit unsorted and badly updated but it's for me and while I don't mind someone else using it, it's primarily intended for my eyes and thus styled in a way for me to enjoy.

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The Recombinant Follicle Stimulating Hormone

In vitro fertilisation (IVF) is one of the several techniques being used for the treatment of infertility. In the early days it was used for treatment of infertility caused by inoperable tubal blockage. Through the years it became evident that a wider range of infertility patients can be treated by IVF.

In order to obtain ova for IVF, controlled ovarian hyperstimulation (COH) for ovulation induction is performed. COH results in more ova being available leading to better pregnancy rates and less side effects. Several substances are available to induce ovulation: clomiphen citrate, human menopausal gonadotrophin (hMG), human chorionic gonadotrophin (hCG), etc. Recently a recombinant follicle stimulation hormone (rFSH) has been developed which gives hope for even better results.

Follicle stimulating hormone (FSH) can be obtained by several techniques. One of them is by purifying urine from menopausal women and extract FSH and luteinizing hormone (LH). But LH may have a negative effect on ovulation induction. Therefore it is necessary to extract only FSH from the urine. Another technique to purify FSH is by using recombinant DNA technique.1 This technique has better results as it is not contaminated with other hormones and differences among batches will minimise.

An effective method of treatment can be found at:

In spite of infertility treatment, ovulation induction is also used to treat diseases such as polycystic ovary syndrome (PCO syndrome). PCO can be defined as LH-dependent hyperandrogenism. The syndrome has abnormalities in four endocrinologic active compartments :

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